Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.S240F

c.719C>T

Surrounding Variants

1 paper

NM_002467.6

p.S241_L255del15

c.721_764del45

1 paper

NM_002467.6

p.S240S

c.720C>T

1 paper

NM_002467.6

p.S241delFs

c.721delT

1 paper

NM_002467.6

p.S241T

c.721T>A

1 paper

NM_002467.6

p.S241P

c.721T>C

1 paper

NM_002467.6

p.S241A

c.721T>G

4 papers

NM_002467.6

p.S241L

c.722C>T

1 paper

NM_002467.6

p.L239V

c.715C>G

1 paper

NM_002467.6

p.L239F

c.715C>T

1 paper

NM_002467.6

p.S241S

c.723G>A

2 papers

NM_002467.6

p.T242M

c.725C>T

1 paper

NM_002467.6

p.E243del1

c.727_728delGAG