Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.P252S

c.754C>T

Surrounding Variants

2 papers

NM_002467.6

p.P252T

c.754C>A

4 papers

NM_002467.6

p.E251A

c.752A>C

2 papers

NM_002467.6

p.E251K

c.751G>A

2 papers

NM_002467.6

p.E251delins

c.751_752delinsTG

1 paper

NM_002467.6

p.L253P

c.758T>C

1 paper

NM_002467.6

p.P250R

c.749C>G

1 paper

NM_002467.6

p.P250L

c.749C>T

1 paper

NM_002467.6

p.V254L

c.760G>C

1 paper

NM_002467.6

p.V254L

c.760G>T

4 papers

NM_002467.6

p.S249R

c.747C>A

4 papers

NM_002467.6

p.S249R

c.747C>G

1 paper

NM_002467.6

p.V254E

c.761T>A