Varaico: Literature-Extracted Genetic Variants

MYC

2,231 papers

RefSeq Summary

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the ...

Pfam Domains

Myc_Naa 17–360UCSCMyc amino-terminal region

HLHaa 370–422UCSCHelix-loop-helix DNA-binding domain

Myc-LZaa 423–453UCSCMyc leucine zipper domain

Gene Aliases

HGNC Name

MYC proto-oncogene, bHLH transcription factor

HGNC Alias Symbols

c-Myc; bHLHe39; MYCC

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002467.6

p.E258D

c.774G>C

Surrounding Variants

1 paper

NM_002467.6

p.E258D

c.774G>T

1 paper

NM_002467.6

p.T259_P260insCCT

c.775_779ins9

1 paper

NM_002467.6

p.E258A

c.773A>C

1 paper

NM_002467.6

p.T259P

c.775A>C

1 paper

NM_002467.6

p.E258G

c.773A>G

1 paper

NM_002467.6

p.T259A

c.775A>G

1 paper

NM_002467.6

p.E258V

c.773A>T

2 papers

NM_002467.6

p.T259I

c.776C>T

1 paper

NM_002467.6

p.E258K

c.772G>A

1 paper

NM_002467.6

p.P260T

c.778C>A

5 papers

NM_002467.6

p.P260A

c.778C>G

2 papers

NM_002467.6

p.P260L

c.779C>T