Varaico: Literature-Extracted Genetic Variants

Gene:MYCN
Variant:p.P237L

MYCN

596 papers

RefSeq Summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order t...

Pfam Domains

Myc_Naa 7–372UCSCMyc amino-terminal region
HLHaa 382–434UCSCHelix-loop-helix DNA-binding domain

Gene Aliases

HGNC Name

MYCN proto-oncogene, bHLH transcription factor

HGNC Previous Symbol

NMYC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005378.6
p.P237L
c.710C>T
Surrounding Variants
1 paper
NM_005378.6
p.P237R
c.710C>G
1 paper
NM_005378.6
p.R238L
c.713G>T
1 paper
NM_005378.6
p.P236T
c.706C>A
1 paper
NM_005378.6
p.P236S
c.706C>T
1 paper
NM_005378.6
p.A235P
c.703G>C
1 paper
NM_005378.6
p.A235S
c.703G>T
1 paper
NM_005378.6
p.G240S
c.718G>A
1 paper
NM_005378.6
p.G240D
c.719G>A
1 paper
NM_005378.6
p.G233A
c.698G>C
2 papers
NM_005378.6
p.G230V
c.689G>T
1 paper
NM_005378.6
p.A229V
c.686C>T
3 papers
NM_005378.6
p.P228fs
c.682_683fs
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."