Varaico: Literature-Extracted Genetic Variants

Gene:MYCN
Variant:p.A354V

MYCN

596 papers

RefSeq Summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order t...

Pfam Domains

Myc_Naa 7–372UCSCMyc amino-terminal region
HLHaa 382–434UCSCHelix-loop-helix DNA-binding domain

Gene Aliases

HGNC Name

MYCN proto-oncogene, bHLH transcription factor

HGNC Previous Symbol

NMYC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_005378.6
p.A354V
c.1061C>T
Surrounding Variants
1 paper
NM_005378.6
p.A354insFs
c.1061dupC
1 paper
NM_005378.6
p.S355fs
c.1063_1064fs
1 paper
NM_005378.6
p.S355_P356insGT
c.1063_1067ins6
1 paper
NM_005378.6
p.E353K
c.1057G>A
1 paper
NM_005378.6
p.R357fs
c.1069_1070fs
2 papers
NM_005378.6
p.R357C
c.1069C>T
3 papers
NM_005378.6
p.R357H
c.1070G>A
1 paper
NM_005378.6
p.R357insFs
c.1070_1071insGT
3 papers
NM_005378.6
p.K351*
c.1051A>T
1 paper
NM_005378.6
p.P358S
c.1072C>T
1 paper
NM_005378.6
p.P358L
c.1073C>T
1 paper
NM_005378.6
p.L359V
c.1075C>G
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