Varaico: Literature-Extracted Genetic Variants

Gene:MYCN
Variant:p.R398W

MYCN

596 papers

RefSeq Summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order t...

Pfam Domains

Myc_Naa 7–372UCSCMyc amino-terminal region
HLHaa 382–434UCSCHelix-loop-helix DNA-binding domain

Gene Aliases

HGNC Name

MYCN proto-oncogene, bHLH transcription factor

HGNC Previous Symbol

NMYC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
6 papers
NM_005378.6
p.R398W
c.1192C>T
Surrounding Variants
1 paper
NM_005378.6
p.R398Q
c.1193G>A
1 paper
NM_005378.6
p.L397F
c.1189C>T
1 paper
NM_005378.6
p.S399F
c.1196C>T
1 paper
NM_005378.6
p.D396N
c.1186G>A
2 papers
NM_005378.6
p.S400N
c.1199G>A
1 paper
NM_005378.6
p.N395D
c.1183A>G
5 papers
NM_005378.6
p.R394H
c.1181G>A
1 paper
NM_005378.6
p.R394L
c.1181G>T
2 papers
NM_005378.6
p.R394G
c.1180C>G
1 paper
NM_005378.6
p.L402F
c.1204C>T
1 paper
NM_005378.6
p.T403insFs
c.1207dupA
1 paper
NM_005378.6
p.T403delFs
c.1207delA
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