Varaico: Literature-Extracted Genetic Variants

Gene:MYCN
Variant:p.K425insFs

MYCN

596 papers

RefSeq Summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order t...

Pfam Domains

Myc_Naa 7–372UCSCMyc amino-terminal region
HLHaa 382–434UCSCHelix-loop-helix DNA-binding domain

Gene Aliases

HGNC Name

MYCN proto-oncogene, bHLH transcription factor

HGNC Previous Symbol

NMYC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005378.6
p.K425insFs
c.1274dupA
Surrounding Variants
3 papers
NM_005378.6
p.L423L
c.1269G>A
1 paper
NM_005378.6
p.L423F
c.1269G>C
1 paper
NM_005378.6
p.L423F
c.1269G>T
1 paper
NM_005378.6
p.K425delFs
c.1274delA
1 paper
NM_005378.6
p.K424N
c.1272A>C
1 paper
NM_005378.6
p.K425fs
c.1273_1274fs
1 paper
NM_005378.6
p.K425fs
c.1273_1274fs
1 paper
NM_005378.6
p.K425R
c.1274A>G
1 paper
NM_005378.6
p.A426T
c.1276G>A
1 paper
NM_005378.6
p.A426fs
c.1276_1277fs
1 paper
NM_005378.6
p.V421D
c.1262T>A
1 paper
NM_005378.6
p.A418D
c.1253C>A
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