Varaico: Literature-Extracted Genetic Variants

Gene:MYCN
Variant:p.C464Y

MYCN

596 papers

RefSeq Summary

This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order t...

Pfam Domains

Myc_Naa 7–372UCSCMyc amino-terminal region
HLHaa 382–434UCSCHelix-loop-helix DNA-binding domain

Gene Aliases

HGNC Name

MYCN proto-oncogene, bHLH transcription factor

HGNC Previous Symbol

NMYC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005378.6
p.C464Y
c.1391G>A
Surrounding Variants
1 paper
NM_005378.6
p.R462G
c.1384C>G
1 paper
NM_005378.6
p.A461T
c.1381G>A
1 paper
NM_005378.6
p.E459K
c.1375G>A
1 paper
NM_005378.6
p.L455L
c.1363C>T
1 paper
NM_005378.6
p.L454F
c.1362G>C
1 paper
NM_005378.6
p.L454F
c.1362G>T
1 paper
NM_005378.6
p.Q451*
c.1351C>T
1 paper
NM_005378.6
p.L447M
c.1339T>A
1 paper
NM_005378.6
p.K446insFs
c.1337_1338insTA
1 paper
NM_005378.6
p.K446fs
c.1336_1337fs
1 paper
NM_005378.6
p.E445K
c.1333G>A
1 paper
NM_005378.6
p.K446delFs
c.1338delA
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