Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.A8A

c.24G>A

Surrounding Variants

1 paper

NM_002468.5

p.A8T

c.22G>A

1 paper

NM_002468.5

p.A11_T17delFs

c.33_49del17

1 paper

NM_002468.5

p.P6delFs

c.18delC

1 paper

NM_002468.5

p.G5D

c.14G>A

1 paper

NM_002468.5

p.G5V

c.14G>T

3 papers

NM_002468.5

p.G4_S10delFs

c.10_28del19

1 paper

NM_002468.5

p.A3V

c.8C>T

2 papers

NM_002468.5

p.V14I

c.40G>A

1 paper

NM_002468.5

p.A3S

c.7G>T

1 paper

NM_002468.5

p.V14D

c.41T>A

1 paper

NM_002468.5

p.S15insFs

c.43_44insA

1 paper

NM_002468.5

p.A2S

c.4G>T