Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.L33L

c.97C>T

Surrounding Variants

1 paper

NM_002468.5

p.L33V

c.97C>G

8 papers

NM_002468.5

p.S34Y

c.101C>A

1 paper

NM_002468.5

p.S34C

c.101C>G

2 papers

NM_002468.5

p.S34F

c.101C>T

1 paper

NM_002468.5

p.S34S

c.102T>C

1 paper

NM_002468.5

p.L35M

c.103C>A

1 paper

NM_002468.5

p.L35V

c.103C>G

1 paper

NM_002468.5

p.L35P

c.104T>C

1 paper

NM_002468.5

p.R30W

c.88C>T

1 paper

NM_002468.5

p.R28R

c.84A>T

1 paper

NM_002468.5

p.L37*

c.110T>A

1 paper

NM_002468.5

p.N38S

c.113A>G