Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002468.5

p.E65del1

c.193_194delGAG

Surrounding Variants

1 paper

NM_002468.5

p.L64L

c.192G>A

1 paper

NM_002468.5

p.L64_A68delFs

c.190_202del13

2 papers

NM_002468.5

p.E65K

c.193G>A

1 paper

NM_002468.5

p.Q63*

c.187C>T

2 papers

NM_002468.5

p.T66del1

c.196_198delACA

1 paper

NM_002468.5

p.T71fs

c.211_212fs

1 paper

NM_002468.5

p.T71N

c.212C>A

1 paper

NM_002468.5

p.T71_G72insFs

c.213_214insT

1 paper

NM_002468.5

p.T71I

c.212C>T

1 paper

NM_002468.5

p.E57delFs

c.170delA

1 paper

NM_002468.5

p.G72V

c.215G>T

1 paper

NM_002468.5

p.F56C

c.167T>G