Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.G80_R81del2

c.238_242del6

Surrounding Variants

1 paper

NM_002468.5

p.R81S

c.241C>A

1 paper

NM_002468.5

p.R81C

c.241C>T

1 paper

NM_002468.5

p.A77_W78delFs

c.231_232delCT

1 paper

NM_002468.5

p.P82L

c.245C>T

1 paper

NM_002468.5

p.D76A

c.227A>C

1 paper

NM_002468.5

p.D76H

c.226G>C

1 paper

NM_002468.5

p.A84V

c.251C>T

2 papers

NM_002468.5

p.S85P

c.253T>C

1 paper

NM_002468.5

p.L74M

c.220C>A

1 paper

NM_002468.5

p.L74delFs

c.220delC

1 paper

NM_002468.5

p.V86L

c.256G>C

1 paper

NM_002468.5

p.V86L

c.256G>T