Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.P158L

c.473C>T

Surrounding Variants

1 paper

NM_002468.5

p.E159delFs

c.476_477delAG

1 paper

NM_002468.5

p.E159G

c.476A>G

1 paper

NM_002468.5

p.M157T

c.470T>C

1 paper

NM_002468.5

p.M157L

c.469A>C

1 paper

NM_002468.5

p.M157L

c.469A>T

1 paper

NM_002468.5

p.M157_E159del3

c.469_476del9

2 papers

NM_002468.5

p.R160H

c.479G>A

1 paper

NM_002468.5

p.R160P

c.479G>C

1 paper

NM_002468.5

p.D162A

c.485A>C

1 paper

NM_002468.5

p.D162E

c.486T>A

1 paper

NM_002468.5

p.D162E

c.486T>G

2 papers

NM_002468.5

p.A163T

c.487G>A