Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.I172I

c.516C>T

Surrounding Variants

1 paper

NM_002468.5

p.Q173_F174delFs

c.517_520del4

1 paper

NM_002468.5

p.D171N

c.511G>A

1 paper

NM_002468.5

p.S170R

c.508A>C

1 paper

NM_002468.5

p.M178I

c.534G>A

1 paper

NM_002468.5

p.M178I

c.534G>C

1 paper

NM_002468.5

p.M178I

c.534G>T

1 paper

NM_002468.5

p.C166Y

c.497G>A

1 paper

NM_002468.5

p.I179N

c.536T>A

1 paper

NM_002468.5

p.I165V

c.493A>G

1 paper

NM_002468.5

p.R180Q

c.539G>A

1 paper

NM_002468.5

p.Q181K

c.541C>A

1 paper

NM_002468.5

p.Q181delFs

c.542delA