Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.R180Q

c.539G>A

Surrounding Variants

1 paper

NM_002468.5

p.Q181K

c.541C>A

1 paper

NM_002468.5

p.Q181delFs

c.542delA

1 paper

NM_002468.5

p.I179N

c.536T>A

1 paper

NM_002468.5

p.L182V

c.544C>G

1 paper

NM_002468.5

p.M178I

c.534G>A

1 paper

NM_002468.5

p.M178I

c.534G>C

1 paper

NM_002468.5

p.M178I

c.534G>T

1 paper

NM_002468.5

p.E183A

c.548A>C

1 paper

NM_002468.5

p.E183G

c.548A>G

1 paper

NM_002468.5

p.Q184*

c.550C>T

1 paper

NM_002468.5

p.Q184R

c.551A>G

1 paper

NM_002468.5

p.N186N

c.558C>T