Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.D197E

c.591T>G

Surrounding Variants

1 paper

NM_002468.5

p.D197E

c.591T>A

1 paper

NM_002468.5

p.R196R

c.588C>G

10 papers

NM_002468.5

p.R196C

c.586C>T

2 papers

NM_002468.5

p.L199Q

c.596T>A

2 papers

NM_002468.5

p.D195A

c.584A>C

2 papers

NM_002468.5

p.R196_V198del3

c.586_593del9

1 paper

NM_002468.5

p.P200A

c.598C>G

2 papers

NM_002468.5

p.P200H

c.599C>A

1 paper

NM_002468.5

p.D195delFs

c.584delA

1 paper

NM_002468.5

p.G201A

c.602G>C

1 paper

NM_002468.5

p.G201V

c.602G>T

1 paper

NM_002468.5

p.V193M

c.577G>A