Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_002468.5

p.S209R

c.625A>C

Surrounding Variants

3 papers

NM_002468.5

p.S209R

c.627T>A

3 papers

NM_002468.5

p.S209R

c.627T>G

1 paper

NM_002468.5

p.E210K

c.628G>A

1 paper

NM_002468.5

p.L211delFs

c.631_632delCT

1 paper

NM_002468.5

p.I207T

c.620T>C

1 paper

NM_002468.5

p.L211fs

c.631_632fs

1 paper

NM_002468.5

p.S206S

c.618T>A

10 papers

NM_002468.5

p.S206C

c.617C>G

1 paper

NM_002468.5

p.W205*

c.614G>A

1 paper

NM_002468.5

p.E213K

c.637G>A

1 paper

NM_002468.5

p.E213_K214insT

c.637_641ins3

8 papers

NM_002468.5

p.W205R

c.613T>C