Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_002468.5

p.S230N

c.689G>A

Surrounding Variants

1 paper

NM_002468.5

p.K231delFs

c.691delA

1 paper

NM_002468.5

p.K231_E232del2

c.691_695del6

1 paper

NM_002468.5

p.K231*

c.691A>T

1 paper

NM_002468.5

p.Y227C

c.680A>G

2 papers

NM_002468.5

p.Y227F

c.680A>T

1 paper

NM_002468.5

p.D234A

c.701A>C

1 paper

NM_002468.5

p.D226G

c.677A>G

1 paper

NM_002468.5

p.D226delFs

c.677delA

1 paper

NM_002468.5

p.D225G

c.674A>G

2 papers

NM_002468.5

p.V222V

c.666T>G

1 paper

NM_002468.5

p.K238T

c.713A>C

1 paper

NM_002468.5

p.F239insFs

c.716_717insT