Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

42 papers

NM_002468.5

p.L252P

c.755T>C

Surrounding Variants

1 paper

NM_002468.5

p.R251Q

c.752G>A

2 papers

NM_002468.5

p.R251*

c.751C>T

1 paper

NM_002468.5

p.P254L

c.761C>T

2 papers

NM_002468.5

p.Q249P

c.746A>C

1 paper

NM_001172567.2

p.Q257R

c.770A>G

1 paper

NM_002468.5

p.I255M

c.765C>G

1 paper

NM_002468.5

p.K256M

c.767A>T

1 paper

NM_002468.5

p.A247D

c.740C>A

4 papers

NM_002468.5

p.M260T

c.779T>C

2 papers

NM_002468.5

p.K262_E263del0

c.784_789del6

1 paper

NM_002468.5

p.K261_F264del0

c.782_790del9

1 paper

NM_002468.5

p.K261R

c.782A>G