Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.F264S

c.791T>C

Surrounding Variants

1 paper

NM_002468.5

p.P265S

c.793C>T

1 paper

NM_002468.5

p.E263E

c.789G>A

3 papers

NM_002468.5

p.P265L

c.794C>T

1 paper

NM_002468.5

p.S266S

c.798C>T

1 paper

NM_002468.5

p.K261R

c.782A>G

2 papers

NM_002468.5

p.K262_E263del0

c.784_789del6

1 paper

NM_002468.5

p.K261_F264del0

c.782_790del9

1 paper

NM_002468.5

p.L268L

c.802C>T

4 papers

NM_002468.5

p.M260T

c.779T>C

1 paper

NM_002468.5

p.F270insFs

c.810dupC

1 paper

NM_002468.5

p.I271F

c.811A>T

1 paper

NM_002468.5

p.K256M

c.767A>T