Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.C274delFs

c.822delC

Surrounding Variants

1 paper

NM_002468.5

p.V273V

c.819C>T

1 paper

NM_002468.5

p.D275N

c.823G>A

15 papers

NM_002468.5

p.V273A

c.818T>C

1 paper

NM_002468.5

p.I271F

c.811A>T

1 paper

NM_002468.5

p.F270insFs

c.810dupC

1 paper

NM_002468.5

p.L268L

c.802C>T

4 papers

NM_002468.5

p.T281P

c.841A>C

1 paper

NM_002468.5

p.S266S

c.798C>T

1 paper

NM_002468.5

p.K282R

c.845A>G

1 paper

NM_002468.5

p.K282I

c.845A>T

1 paper

NM_002468.5

p.S283delins

c.847delinsTGGATGT

3 papers

NM_002468.5

p.P265L

c.794C>T