Varaico: Literature-Extracted Genetic Variants

MYD88

369 papers

RefSeq Summary

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and To...

Pfam Domains

Deathaa 30–108UCSCDeath domain

Deathaa 43–121UCSCDeath domain

TIR_2aa 163–292UCSCTIR domain

Gene Aliases

HGNC Name

MYD88 innate immune signal transduction adaptor

HGNC Previous Names

myeloid differentiation primary response gene (88); myeloid differentiation primary response 88

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002468.5

p.K282I

c.845A>T

Surrounding Variants

1 paper

NM_002468.5

p.K282R

c.845A>G

1 paper

NM_002468.5

p.S283delins

c.847delinsTGGATGT

4 papers

NM_002468.5

p.T281P

c.841A>C

1 paper

NM_002468.5

p.F285_L295del0

c.853_885del33

1 paper

NM_002468.5

p.F285fs

c.853_854fs

1 paper

NM_002468.5

p.F285_L295del0

c.854_883del30

1 paper

NM_002468.5

p.F285delFs

c.855delC

1 paper

NM_002468.5

p.W286_P296del0

c.856_888del33

1 paper

NM_002468.5

p.F285F

c.855C>T

1 paper

NM_002468.5

p.T287_L293del0

c.859_879del21

1 paper

NM_002468.5

p.R288_S294del0

c.862_882del21

1 paper

NM_002468.5

p.R288G

c.862C>G