Varaico: Literature-Extracted Genetic Variants

MYH10

183 papers

RefSeq Summary

This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-10 (MYO10). Myosins are actin-de...

Pfam Domains

Myosin_Naa 31–76UCSCMyosin N-terminal SH3-like domain

Myosin_headaa 87–771UCSCMyosin head (motor domain)

IQaa 787–807UCSCIQ calmodulin-binding motif

IQaa 797–817UCSCIQ calmodulin-binding motif

Myosin_tail_1aa 848–1928UCSCMyosin tail

Gene Aliases

HGNC Name

myosin heavy chain 10

HGNC Alias Symbol

NMMHCB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_001256012.3

p.T668fs

c.2002_2003fs

Surrounding Variants

2 papers

NM_001256012.3

p.T668delFs

c.2002delT

1 paper

NM_001256012.3

p.E667K

c.1999G>A

1 paper

NM_001256012.3

p.V657M

c.1969G>A

2 papers

NM_001256012.3

p.G679D

c.2036G>A

1 paper

NM_001256012.3

p.F681_R682insGCT

c.2041_2045ins9

1 paper

NM_001256012.3

p.D654G

c.1961A>G

1 paper

NM_001256012.3

p.D654H

c.1960G>C

1 paper

NM_001256012.3

p.K689E

c.2065A>G

1 paper

NM_001256012.3

p.T698A

c.2092A>G

1 paper

NM_001256012.3

p.R700Q

c.2099G>A

1 paper

NM_001256012.3

p.T702N

c.2105C>A

1 paper

NM_001256012.3

p.L730R

c.2189T>G