Varaico: Literature-Extracted Genetic Variants

MYH7

2,286 papers

RefSeq Summary

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit o...

Pfam Domains

Myosin_Naa 32–76UCSCMyosin N-terminal SH3-like domain

Myosin_headaa 87–766UCSCMyosin head (motor domain)

Myosin_tail_1aa 843–1924UCSCMyosin tail

Gene Aliases

HGNC Name

myosin heavy chain 7

HGNC Previous Symbols

CMH1; MPD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000257.4

p.I590V

c.1768A>G

Surrounding Variants

1 paper

NM_000257.4

p.N589N

c.1767C>T

4 papers

NM_000257.4

p.N589I

c.1766A>T

1 paper

NM_000257.4

p.N589D

c.1765A>G

1 paper

NM_000257.4

p.Y588*

c.1764C>G

1 paper

NM_000257.4

p.Y588*

c.1764C>A

9 papers

NM_000257.4

p.Y588F

c.1763A>T

2 papers

NM_000257.4

p.G592S

c.1774G>A

2 papers

NM_000257.4

p.D587V

c.1760A>T

4 papers

NM_000257.4

p.D587H

c.1759G>C

5 papers

NM_000257.4

p.D587N

c.1759G>A

5 papers

NM_000257.4

p.V586A

c.1757T>C

2 papers

NM_000257.4

p.V586M

c.1756G>A