Varaico: Literature-Extracted Genetic Variants

MYH7

2,286 papers

RefSeq Summary

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit o...

Pfam Domains

Myosin_Naa 32–76UCSCMyosin N-terminal SH3-like domain

Myosin_headaa 87–766UCSCMyosin head (motor domain)

Myosin_tail_1aa 843–1924UCSCMyosin tail

Gene Aliases

HGNC Name

myosin heavy chain 7

HGNC Previous Symbols

CMH1; MPD1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000257.4

p.T441R

c.1322C>G

Surrounding Variants

31 papers

NM_000257.4

p.T441M

c.1322C>T

40 papers

NM_000257.4

p.R442C

c.1324C>T

27 papers

NM_000257.4

p.R442G

c.1324C>G

1 paper

NM_000257.4

p.V440A

c.1319T>C

5 papers

NM_000257.4

p.R442L

c.1325G>T

1 paper

NM_000257.4

p.R442P

c.1325G>C

16 papers

NM_000257.4

p.R442H

c.1325G>A

9 papers

NM_000257.4

p.V440M

c.1318G>A

1 paper

NM_000257.4

p.M439I

c.1317G>T

1 paper

NM_000257.4

p.M439I

c.1317G>C

1 paper

NM_000257.4

p.M439I

c.1317G>A

2 papers

NM_000257.4

p.I443V

c.1327A>G