Varaico: Literature-Extracted Genetic Variants

MYO10

186 papers

RefSeq Summary

This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myos...

Pfam Domains

SH3_19aa 7–58UCSCMyosin X N-terminal SH3 domain

Myosin_headaa 65–727UCSCMyosin head (motor domain)

IQaa 743–763UCSCIQ calmodulin-binding motif

IQaa 767–786UCSCIQ calmodulin-binding motif

IQaa 789–809UCSCIQ calmodulin-binding motif

MYO10_CCaa 882–933UCSCUnconventional myosin-X coiled coil domain

Gene Aliases

HGNC Name

myosin X

HGNC Alias Symbols

KIAA0799; MyoX

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_012334.3

p.Q1578*

c.4732C>T

Surrounding Variants

1 paper

NM_012334.3

p.G1561V

c.4682G>T

1 paper

NM_012334.3

p.L1610R

c.4829T>G

1 paper

NM_012334.3

p.S1642N

c.4925G>A

1 paper

NM_012334.3

p.K1654N

c.4962A>T

1 paper

NM_012334.3

p.K1654N

c.4962A>C

1 paper

NM_012334.3

p.P1546A

c.4636C>G

1 paper

NM_012334.3

p.L1544fs

c.4630_4631fs

1 paper

NM_012334.3

p.Y1535_P1543insFs

c.4604_4628dup25

1 paper

NM_012334.3

p.P1543L

c.4628C>T

4 papers

NM_012334.3

p.S1520L

c.4559C>T

1 paper

NM_012334.3

p.N1519fs

c.4555_4556fs

7 papers

NM_012334.3

p.S1663T

c.4988G>C