Varaico: Literature-Extracted Genetic Variants

MYO10

186 papers

RefSeq Summary

This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myos...

Pfam Domains

SH3_19aa 7–58UCSCMyosin X N-terminal SH3 domain

Myosin_headaa 65–727UCSCMyosin head (motor domain)

IQaa 743–763UCSCIQ calmodulin-binding motif

IQaa 767–786UCSCIQ calmodulin-binding motif

IQaa 789–809UCSCIQ calmodulin-binding motif

MYO10_CCaa 882–933UCSCUnconventional myosin-X coiled coil domain

Gene Aliases

HGNC Name

myosin X

HGNC Alias Symbols

KIAA0799; MyoX

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_012334.3

p.A758V

c.2273C>T

Surrounding Variants

4 papers

NM_012334.3

p.R759Q

c.2276G>A

1 paper

NM_012334.3

p.M747T

c.2240T>C

2 papers

NM_012334.3

p.A745V

c.2234C>T

4 papers

NM_012334.3

p.R759Q

c.2276G>A

1 paper

NM_012334.3

p.L781R

c.2342T>G

1 paper

NM_012334.3

p.R832Q

c.2495G>A

1 paper

NM_012334.3

p.R837Splc

c.2511-8A>G

1 paper

NM_012334.3

p.E840K

c.2518G>A

1 paper

NM_012334.3

p.R843Q

c.2528G>A

1 paper

NM_012334.3

p.A850T

c.2548G>A

1 paper

NM_012334.3

p.R876C

c.2626C>T

1 paper

NM_012334.3

p.E877Q

c.2629G>C