Varaico: Literature-Extracted Genetic Variants

MYO10

186 papers

RefSeq Summary

This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myos...

Pfam Domains

SH3_19aa 7–58UCSCMyosin X N-terminal SH3 domain

Myosin_headaa 65–727UCSCMyosin head (motor domain)

IQaa 743–763UCSCIQ calmodulin-binding motif

IQaa 767–786UCSCIQ calmodulin-binding motif

IQaa 789–809UCSCIQ calmodulin-binding motif

MYO10_CCaa 882–933UCSCUnconventional myosin-X coiled coil domain

Gene Aliases

HGNC Name

myosin X

HGNC Alias Symbols

KIAA0799; MyoX

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_012334.3

p.G672fs

c.2014_2015fs

Surrounding Variants

1 paper

NM_012334.3

p.R669L

c.2006G>T

1 paper

NM_012334.3

p.R676*

c.2026C>T

3 papers

NM_012334.3

p.V652insFs

c.1956dupT

3 papers

NM_012334.3

p.V653fs

c.1957_1958fs

1 paper

NM_012334.3

p.L693V

c.2077C>G

1 paper

NM_012334.3

p.L695insFs

c.2083dupC

1 paper

NM_012334.3

p.R700Q

c.2099G>A

1 paper

NM_012334.3

p.S705N

c.2114G>A

1 paper

NM_012334.3

p.N714D

c.2140A>G

2 papers

NM_012334.3

p.A745V

c.2234C>T

1 paper

NM_012334.3

p.M747T

c.2240T>C

1 paper

NM_012334.3

p.A758V

c.2273C>T