Varaico: Literature-Extracted Genetic Variants

MYO10

186 papers

RefSeq Summary

This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-10 (MYH10). Unconventional myos...

Pfam Domains

SH3_19aa 7–58UCSCMyosin X N-terminal SH3 domain

Myosin_headaa 65–727UCSCMyosin head (motor domain)

IQaa 743–763UCSCIQ calmodulin-binding motif

IQaa 767–786UCSCIQ calmodulin-binding motif

IQaa 789–809UCSCIQ calmodulin-binding motif

MYO10_CCaa 882–933UCSCUnconventional myosin-X coiled coil domain

Gene Aliases

HGNC Name

myosin X

HGNC Alias Symbols

KIAA0799; MyoX

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_012334.3

p.N531K

c.1593C>A

Surrounding Variants

1 paper

NM_012334.3

p.N531K

c.1593C>G

1 paper

NM_012334.3

p.H532_K536del5

c.1594_1607del15

1 paper

NM_012334.3

p.L524_A529delFs

c.1571_1587del17

1 paper

NM_012334.3

p.L524fs

c.1570_1571fs

1 paper

NM_012334.3

p.A515V

c.1544C>T

1 paper

NM_012334.3

p.A504V

c.1511C>T

1 paper

NM_012334.3

p.D571N

c.1711G>A

1 paper

NM_012334.3

p.N574S

c.1721A>G

1 paper

NM_012334.3

p.R577K

c.1730G>A

1 paper

NM_012334.3

p.E497E

c.1491G>A

1 paper

NM_012334.3

p.N489S

c.1466A>G

1 paper

NM_012334.3

p.W486C

c.1458G>T