Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

1–12 of 354 variants

13 papers

NM_003743.5

p.P1272S

c.3814C>T

5 papers

NM_003743.5

p.R572S

c.1716A>C

5 papers

NM_003743.5

p.R572S

c.1716A>T

5 papers

NM_003743.5

p.L1376P

c.4127T>C

4 papers

NM_003743.5

p.N1332S

c.3995A>G

3 papers

NM_003743.5

p.T154T

c.462G>C

3 papers

NM_003743.5

p.L346F

c.1036C>T

3 papers

NM_003743.5

p.P504P

c.1512A>T

3 papers

NM_003743.5

p.S738L

c.2213C>T

3 papers

NM_003743.5

p.L1267L

c.3801T>G

2 papers

NM_003743.5

p.V94V

c.282A>G

2 papers

NM_003743.5

p.V156I

c.466G>A