Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003743.5

p.K63R

c.188A>G

Surrounding Variants

1 paper

NM_003743.5

p.P64R

c.191C>G

1 paper

NM_003743.5

p.S59I

c.176G>T

1 paper

NM_003743.5

p.K72E

c.214A>G

1 paper

NM_003743.5

p.V74I

c.220G>A

1 paper

NM_003743.5

p.L50R

c.149T>G

1 paper

NM_003743.5

p.L46R

c.137T>G

1 paper

NM_003743.5

p.L46delFs

c.136delC

1 paper

NM_003743.5

p.Y42_L43insFs

c.126_127insAA

1 paper

NM_003743.5

p.Q85Q

c.255A>G

1 paper

NM_003743.5

p.E39Fs

c.117delinsTTFs

1 paper

NM_003743.5

p.Q38delFs

c.112delC

1 paper

NM_003743.5

p.R36W

c.106A>T