Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003743.5

p.K109R

c.326A>G

Surrounding Variants

1 paper

NM_003743.5

p.S111F

c.332C>T

1 paper

NM_003743.5

p.G105E

c.314G>A

1 paper

NM_003743.5

p.L115V

c.343C>G

1 paper

NM_003743.5

p.S103_Q104insFs

c.309_310insAA

1 paper

NM_003743.5

p.S101*

c.302C>A

1 paper

NM_003743.5

p.D98E

c.294C>G

2 papers

NM_003743.5

p.V94V

c.282A>G

1 paper

NM_003743.5

p.D93_V94delFs

c.278_281del4

1 paper

NM_003743.5

p.D92E

c.276C>A

1 paper

NM_003743.5

p.T90A

c.268A>G

1 paper

NM_003743.5

p.Q85Q

c.255A>G

1 paper

NM_003743.5

p.V74I

c.220G>A