Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003743.5

p.T154T

c.462G>C

Surrounding Variants

1 paper

NM_003743.5

p.T154S

c.460A>T

2 papers

NM_003743.5

p.V156I

c.466G>A

1 paper

NM_003743.5

p.I159I

c.477A>C

1 paper

NM_003743.5

p.V162M

c.484G>A

1 paper

NM_003743.5

p.H165Q

c.495T>A

1 paper

NM_003743.5

p.H165Q

c.495T>G

1 paper

NM_003743.5

p.V169V

c.507G>A

1 paper

NM_003743.5

p.N171N

c.513T>C

1 paper

NM_003743.5

p.V136M

c.406G>A

1 paper

NM_003743.5

p.L173R

c.518T>G

1 paper

NM_003743.5

p.F135C

c.404T>G

1 paper

NM_003743.5

p.S176_L177insFs

c.528_529insC