Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003743.5

p.S327T

c.979T>A

Surrounding Variants

1 paper

NM_003743.5

p.R320H

c.959G>A

1 paper

NM_003743.5

p.R320P

c.959G>C

1 paper

NM_003743.5

p.R320L

c.959G>T

1 paper

NM_003743.5

p.R320C

c.958C>T

1 paper

NM_003743.5

p.G335Fs

c.1003delinsGAFs

1 paper

NM_003743.5

p.T336I

c.1007C>T

1 paper

NM_003743.5

p.S339S

c.1017C>T

1 paper

NM_003743.5

p.H341R

c.1022A>G

3 papers

NM_003743.5

p.L346F

c.1036C>T

1 paper

NM_003743.5

p.L346R

c.1037T>G

1 paper

NM_003743.5

p.I361I

c.1083T>A

2 papers

NM_003743.5

p.T377N

c.1130C>A