Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003743.5

p.S379F

c.1136C>T

Surrounding Variants

1 paper

NM_003743.5

p.N378K

c.1134T>A

1 paper

NM_003743.5

p.N378K

c.1134T>G

2 papers

NM_003743.5

p.T377N

c.1130C>A

2 papers

NM_003743.5

p.M381R

c.1142T>G

1 paper

NM_003743.5

p.R385G

c.1153C>G

2 papers

NM_003743.5

p.R385*

c.1153C>T

2 papers

NM_003743.5

p.R385Q

c.1154G>A

1 paper

NM_003743.5

p.R385L

c.1154G>T

2 papers

NM_003743.5

p.S389L

c.1166C>T

1 paper

NM_003743.5

p.V390A

c.1169T>C

1 paper

NM_003743.5

p.V390V

c.1170C>T

1 paper

NM_003743.5

p.N391S

c.1172A>G