Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003743.5

p.G442R

c.1324G>C

Surrounding Variants

2 papers

NM_003743.5

p.G442R

c.1324G>A

1 paper

NM_003743.5

p.G442V

c.1325G>T

1 paper

NM_003743.5

p.C443Y

c.1328G>A

1 paper

NM_003743.5

p.C443*

c.1329C>A

1 paper

NM_003743.5

p.S444L

c.1331C>T

1 paper

NM_003743.5

p.G439R

c.1315G>A

1 paper

NM_003743.5

p.G439R

c.1315G>C

1 paper

NM_003743.5

p.Q448K

c.1342C>A

1 paper

NM_003743.5

p.S435G

c.1303A>G

2 papers

NM_003743.5

p.H431R

c.1292A>G

1 paper

NM_003743.5

p.H427Y

c.1279C>T

1 paper

NM_003743.5

p.A460T

c.1378G>A