Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003743.5

p.P489P

c.1467A>T

Surrounding Variants

1 paper

NM_003743.5

p.R490W

c.1468A>T

1 paper

NM_003743.5

p.S482C

c.1445C>G

1 paper

NM_003743.5

p.A498T

c.1492G>A

1 paper

NM_003743.5

p.G478V

c.1433G>T

1 paper

NM_003743.5

p.R502M

c.1505G>T

3 papers

NM_003743.5

p.P504P

c.1512A>T

1 paper

NM_003743.5

p.S474P

c.1420T>C

1 paper

NM_003743.5

p.N505K

c.1515C>A

1 paper

NM_003743.5

p.N505K

c.1515C>G

1 paper

NM_003743.5

p.P467L

c.1400C>T

1 paper

NM_003743.5

p.S513L

c.1538C>T

2 papers

NM_003743.5

p.Q463H

c.1389G>C