Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003743.5

p.R562G

c.1684A>G

Surrounding Variants

1 paper

NM_003743.5

p.Q563R

c.1688A>G

1 paper

NM_003743.5

p.S565N

c.1694G>A

2 papers

NM_003743.5

p.S557T

c.1670G>C

1 paper

NM_003743.5

p.S555F

c.1664C>T

2 papers

NM_003743.5

p.V552I

c.1654G>A

5 papers

NM_003743.5

p.R572S

c.1716A>C

5 papers

NM_003743.5

p.R572S

c.1716A>T

1 paper

NM_003743.5

p.N574Y

c.1720A>T

1 paper

NM_003743.5

p.N549T

c.1646A>C

1 paper

NM_003743.5

p.N549S

c.1646A>G

1 paper

NM_003743.5

p.I575T

c.1724T>C

1 paper

NM_003743.5

p.P548insFs

c.1643_1644insC