Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003743.5

p.E581Q

c.1741G>C

Surrounding Variants

1 paper

NM_003743.5

p.I575T

c.1724T>C

1 paper

NM_003743.5

p.N574Y

c.1720A>T

5 papers

NM_003743.5

p.R572S

c.1716A>C

5 papers

NM_003743.5

p.R572S

c.1716A>T

1 paper

NM_003743.5

p.S590*

c.1769C>A

1 paper

NM_003743.5

p.S590*

c.1769C>G

1 paper

NM_003743.5

p.I591V

c.1771A>G

1 paper

NM_003743.5

p.L592F

c.1776A>C

1 paper

NM_003743.5

p.L592F

c.1776A>T

1 paper

NM_003743.5

p.M595I

c.1785G>A

1 paper

NM_003743.5

p.M595I

c.1785G>C

1 paper

NM_003743.5

p.M595I

c.1785G>T