Varaico: Literature-Extracted Genetic Variants

NCOA1

381 papers

RefSeq Summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other fa...

Pfam Domains

bHLH_NCOAaa 1–77UCSCNuclear receptor coactivators bHLH domain

PASaa 112–189UCSCPAS fold

PAS_11aa 259–370UCSCPAS domain

NCOA_u2aa 467–590UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 628–708UCSCSteroid receptor coactivator

Nuc_rec_co-actaa 924–973UCSCNuclear receptor coactivator

Gene Aliases

HGNC Name

nuclear receptor coactivator 1

HGNC Alias Symbols

SRC1; F-SRC-1; NCoA-1; KAT13A; RIP160; bHLHe74

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_003743.5

p.L1267L

c.3801T>G

Surrounding Variants

13 papers

NM_003743.5

p.P1272S

c.3814C>T

1 paper

NM_003743.5

p.P1273_S1275delFs

c.3819_3823del5

1 paper

NM_003743.5

p.P1261H

c.3782C>A

1 paper

NM_003743.5

p.P1261S

c.3781C>T

1 paper

NM_003743.5

p.P1259L

c.3776C>T

1 paper

NM_003743.5

p.Y1277C

c.3830A>G

1 paper

NM_003743.5

p.Y1277Y

c.3831T>C

1 paper

NM_003743.5

p.P1257L

c.3770C>T

1 paper

NM_003743.5

p.P1280S

c.3838C>T

1 paper

NM_003743.5

p.S1250I

c.3749G>T

1 paper

NM_003743.5

p.Q1286*

c.3856C>T

1 paper

NM_003743.5

p.A1289V

c.3866C>T