Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 588 variants

10 papers

NM_181659.3

p.Q586H

c.1758G>C

9 papers

NM_181659.3

p.Q586H

c.1758G>T

8 papers

NM_181659.3

p.Q1263_Q1264del1

c.3789_3791delGCA

7 papers

NM_181659.3

p.R218C

c.652C>T

7 papers

NM_181659.3

p.S937C

c.2810C>G

7 papers

NM_181659.3

p.Q1276del1

c.3826_3827delCAA

6 papers

NM_181659.3

p.A416_Y417delFs

c.1246_1249del4

6 papers

NM_181659.3

p.M1246del1

c.3736_3738delATG

6 papers

NM_181659.3

p.M1246_Q1249del4

c.3736_3746del12

6 papers

NM_181659.3

p.M1247_Q1249del3

c.3739_3746del9

6 papers

NM_181659.3

p.Q1251_Q1254del0

c.3753_3761del9

5 papers

NM_181659.3

p.F1238_Q1241del0

c.3714_3722del9