Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_181659.3

p.Q188K

c.562C>A

Surrounding Variants

1 paper

NM_181659.3

p.T187insFs

c.560dupC

1 paper

NM_181659.3

p.E186G

c.557A>G

1 paper

NM_181659.3

p.R189S

c.567A>T

2 papers

NM_181659.3

p.S192insFs

c.574dupA

1 paper

NM_181659.3

p.Q190fs

c.568_569fs

1 paper

NM_181659.3

p.Q190H

c.570A>T

1 paper

NM_181659.3

p.H193L

c.578A>T

1 paper

NM_181659.3

p.T194P

c.580A>C

1 paper

NM_181659.3

p.F195S

c.584T>C

1 paper

NM_181659.3

p.N196S

c.587A>G

1 paper

NM_181659.3

p.R198C

c.592C>T

1 paper

NM_181659.3

p.R198H

c.593G>A