Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_181659.3

p.G460V

c.1379G>T

Surrounding Variants

1 paper

NM_181659.3

p.G460R

c.1378G>A

1 paper

NM_181659.3

p.G460R

c.1378G>C

1 paper

NM_181659.3

p.L461F

c.1381C>T

1 paper

NM_181659.3

p.N462S

c.1385A>G

1 paper

NM_181659.3

p.N456S

c.1367A>G

1 paper

NM_181659.3

p.S465_A474del10

c.1393_1421del30

1 paper

NM_181659.3

p.Q455Q

c.1365G>A

1 paper

NM_181659.3

p.P467A

c.1399C>G

1 paper

NM_181659.3

p.P467S

c.1399C>T

1 paper

NM_181659.3

p.P467fs

c.1399_1400fs

1 paper

NM_181659.3

p.S452_S453insFs

c.1356_1357ins4

1 paper

NM_181659.3

p.G469R

c.1405G>A