Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_181659.3

p.R485C

c.1453C>T

Surrounding Variants

1 paper

NM_181659.3

p.P484insFs

c.1451_1452dupCT

1 paper

NM_181659.3

p.R487delFs

c.1459delC

1 paper

NM_181659.3

p.R487_G488insAAC

c.1459_1463ins9

1 paper

NM_181659.3

p.R487_G488ins10

c.1459_1463ins30

1 paper

NM_181659.3

p.R487C

c.1459C>T

1 paper

NM_181659.3

p.P490L

c.1469C>T

1 paper

NM_181659.3

p.Q478*

c.1432C>T

1 paper

NM_181659.3

p.Q477K

c.1429C>A

1 paper

NM_181659.3

p.H495Y

c.1483C>T

1 paper

NM_181659.3

p.Q496K

c.1486C>A

1 paper

NM_181659.3

p.Q496E

c.1486C>G

1 paper

NM_181659.3

p.G472C

c.1414G>T