Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

10 papers

NM_181659.3

p.Q586H

c.1758G>C

Surrounding Variants

9 papers

NM_181659.3

p.Q586H

c.1758G>T

1 paper

NM_181659.3

p.N588D

c.1762A>G

1 paper

NM_181659.3

p.E581G

c.1742A>G

1 paper

NM_181659.3

p.C575Y

c.1724G>A

1 paper

NM_181659.3

p.S601I

c.1802G>T

1 paper

NM_181659.3

p.P570delFs

c.1710delT

1 paper

NM_181659.3

p.S569G

c.1705A>G

1 paper

NM_181659.3

p.G605R

c.1813G>A

1 paper

NM_181659.3

p.K568_S569insA

c.1702_1706ins3

1 paper

NM_181659.3

p.G605E

c.1814G>A

1 paper

NM_181659.3

p.G605V

c.1814G>T

1 paper

NM_181659.3

p.D566N

c.1696G>A