Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_181659.3

p.G605R

c.1813G>A

Surrounding Variants

1 paper

NM_181659.3

p.G605E

c.1814G>A

1 paper

NM_181659.3

p.G605V

c.1814G>T

1 paper

NM_181659.3

p.N608Y

c.1822A>T

1 paper

NM_181659.3

p.S601I

c.1802G>T

1 paper

NM_181659.3

p.Q609*

c.1825C>T

1 paper

NM_181659.3

p.H618D

c.1852C>G

1 paper

NM_181659.3

p.H618Q

c.1854T>A

1 paper

NM_181659.3

p.H618Q

c.1854T>G

1 paper

NM_181659.3

p.N588D

c.1762A>G

10 papers

NM_181659.3

p.Q586H

c.1758G>C

9 papers

NM_181659.3

p.Q586H

c.1758G>T

1 paper

NM_181659.3

p.T626T

c.1878C>G