Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_181659.3

p.C646Y

c.1937G>A

Surrounding Variants

1 paper

NM_181659.3

p.S645S

c.1935T>C

1 paper

NM_181659.3

p.S645_C646delFs

c.1935_1936delTT

1 paper

NM_181659.3

p.S645fs

c.1933_1934fs

1 paper

NM_181659.3

p.S649F

c.1946C>T

1 paper

NM_181659.3

p.L642_D643del2

c.1924_1928del6

1 paper

NM_181659.3

p.P641S

c.1921C>T

1 paper

NM_181659.3

p.S652delFs

c.1954_1955delAG

1 paper

NM_181659.3

p.S652fs

c.1954_1955fs

1 paper

NM_181659.3

p.V653D

c.1958T>A

1 paper

NM_181659.3

p.L637F

c.1911G>T

1 paper

NM_181659.3

p.S636S

c.1908C>G

1 paper

NM_181659.3

p.S635P

c.1903T>C