Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_181659.3

p.P729_R744del16

c.2185_2231del48

Surrounding Variants

1 paper

NM_181659.3

p.Q726H

c.2178G>C

1 paper

NM_181659.3

p.Q726H

c.2178G>T

1 paper

NM_181659.3

p.K732K

c.2196G>A

1 paper

NM_181659.3

p.K723R

c.2168A>G

1 paper

NM_181659.3

p.N734S

c.2201A>G

1 paper

NM_181659.3

p.L737P

c.2210T>C

1 paper

NM_181659.3

p.L737R

c.2210T>G

1 paper

NM_181659.3

p.G719A

c.2156G>C

1 paper

NM_181659.3

p.R739_L741delFs

c.2216_2222del7

1 paper

NM_181659.3

p.S715F

c.2144C>T

1 paper

NM_181659.3

p.S712N

c.2135G>A

1 paper

NM_181659.3

p.S712I

c.2135G>T