Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_181659.3

p.T787I

c.2360C>T

Surrounding Variants

1 paper

NM_181659.3

p.T787delFs

c.2360delC

1 paper

NM_181659.3

p.K786R

c.2357A>G

1 paper

NM_181659.3

p.S790G

c.2368A>G

NM_001174088.2

p.S800G

c.2398A>G

1 paper

NM_181659.3

p.S777A

c.2329T>G

1 paper

NM_181659.3

p.K753Q

c.2257A>C

2 papers

NM_181659.3

p.S752F

c.2255C>T

1 paper

NM_181659.3

p.A750_L751del1

c.2250_2252delACT

1 paper

NM_181659.3

p.D746E

c.2238T>A

1 paper

NM_181659.3

p.D746E

c.2238T>G

1 paper

NM_181659.3

p.D746G

c.2237A>G

1 paper

NM_181659.3

p.R739_L741delFs

c.2216_2222del7

1 paper

NM_181659.3

p.L737P

c.2210T>C