Varaico: Literature-Extracted Genetic Variants

NCOA3

384 papers

RefSeq Summary

The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone a...

Pfam Domains

bHLH_NCOAaa 1–79UCSCNuclear receptor coactivators bHLH domain

PASaa 113–211UCSCPAS fold

PAS_11aa 264–375UCSCPAS domain

NCOA_u2aa 459–572UCSCUnstructured region on nuclear receptor coactivator protein

SRC-1aa 616–704UCSCSteroid receptor coactivator

DUF4927aa 723–810UCSCDomain of unknown function (DUF4927)

Gene Aliases

HGNC Name

nuclear receptor coactivator 3

HGNC Alias Symbols

AIB1; p/CIP; TRAM-1; CAGH16; TNRC16; KAT13B; bHLHe42; SRC-3; SRC3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_181659.3

p.S948F

c.2843C>T

Surrounding Variants

1 paper

NM_181659.3

p.P952R

c.2855C>G

1 paper

NM_181659.3

p.G956S

c.2866G>A

1 paper

NM_181659.3

p.S957C

c.2870C>G

1 paper

NM_181659.3

p.G939E

c.2816G>A

1 paper

NM_181659.3

p.M938R

c.2813T>G

7 papers

NM_181659.3

p.S937C

c.2810C>G

4 papers

NM_181659.3

p.T960T

c.2880A>G

1 paper

NM_181659.3

p.S935*

c.2804C>A

1 paper

NM_181659.3

p.S935*

c.2804C>G

1 paper

NM_181659.3

p.P962S

c.2884C>T

1 paper

NM_181659.3

p.L963V

c.2887C>G

1 paper

NM_181659.3

p.N934delFs

c.2800delA